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Unit 6: The Cell Cycle, Mitosis, and Meiosis

How one cell becomes two identical cells through mitosis, and how sex cells get half the usual chromosome count through meiosis.

8 topics · 26 questions

Each topic is a path, not a menu: work down it in order and every question builds on the one above. Click any of them to watch the answer draw itself.

The Cell Cycle and Interphase

  1. How it worksHow do the G1, S, and G2 phases of interphase each prepare a cell to divide?
  2. Common mistakeWhy isn't interphase a resting phase where the cell does nothing important?
  3. Going furtherWhat happens to a cell that skips checkpoint control during interphase?
Your turn1 of 2
Across a cell's entire life cycle, it spends the vast majority of its time in interphase and only a small fraction actively dividing. Why does a cell spend most of its life not dividing at all?

Mitosis: Making Identical Copies

  1. How it worksWalk me through how chromosomes line up and split apart during prophase, metaphase, anaphase, and telophase.
  2. Common mistakeWhy doesn't mitosis change the number of chromosomes in the resulting cells?
  3. Going furtherWhat happens to a cell's chromosomes if the spindle fibers fail to attach properly during mitosis?
Your turn1 of 2
A cell entering mitosis has 67 chromosomes at the start of G1, and it replicates its DNA during S phase before dividing. How many chromosomes does each of the two daughter cells have once mitosis is complete?

Cytokinesis in Plant and Animal Cells

  1. How it worksHow does a contractile ring pinch an animal cell in two during cytokinesis?
  2. How it worksHow does a plant cell build a cell plate down the middle instead of pinching like an animal cell?
  3. Common mistakeWhy doesn't cytokinesis happen before mitosis finishes dividing the chromosomes?
Your turn1 of 2
Mitosis finishes dividing a cell's chromosomes into two identical sets before cytokinesis begins. Why does cytokinesis need to happen only after mitosis, rather than before mitosis finishes dividing the chromosomes?

Why Sex Cells Need Meiosis

  1. How it worksHow does meiosis cut the chromosome number in half before egg and sperm form?
  2. Common mistakeWhy isn't meiosis just mitosis that happens to make four cells instead of two?
  3. Ties togetherHow does meiosis producing haploid cells connect to fertilization restoring the full chromosome number?
Your turn1 of 2
A species produces gametes with a haploid chromosome number of 30. What is the diploid chromosome number found in its body cells before meiosis begins?

Meiosis I and Meiosis II

  1. How it worksWalk me through how homologous chromosomes separate during meiosis I.
  2. How it worksWalk me through how sister chromatids finally separate during meiosis II.
  3. Worked exampleFind the number of chromosomes in each resulting cell after meiosis I and after meiosis II, starting from 46.
  4. Common mistakeWhy doesn't meiosis II separate homologous chromosomes the way meiosis I does?
Your turn1 of 2
A cell's chromosome number right after meiosis I finishes is 34. Since meiosis II only separates sister chromatids without changing the chromosome count any further, how many chromosomes does a resulting cell have once meiosis II is also complete?

Comparing Mitosis and Meiosis Side by Side

  1. How it worksWalk me through mitosis and meiosis running side by side from the same starting cell to see where the chromosome counts diverge.
  2. Going furtherWhat happens to the final chromosome number if a cell mistakenly runs meiosis's steps where mitosis should happen?
  3. Common mistakeWhy doesn't mitosis produce four genetically different cells the way meiosis does?
  4. Ties togetherHow does the difference between mitosis's two identical cells and meiosis's four unique cells explain why siblings aren't clones?
Your turn1 of 2
The body uses mitosis for ordinary growth and tissue repair, and a completely separate process, meiosis, only for producing sex cells. Why does the body use two entirely different kinds of cell division for these two jobs?

Crossing Over and Genetic Variation

  1. How it worksHow do homologous chromosomes swap matching segments during crossing over in meiosis I?
  2. Going furtherWhat happens to the combination of alleles on a chromosome after crossing over compared to before?
  3. Common mistakeWhy doesn't crossing over change how many genes are on a chromosome, only which alleles travel together?
Your turn1 of 2
You inherit half your DNA from each parent, yet you aren't a straightforward blend or a simple copy of either one. Why are you genetically different from both of your parents even though half your DNA comes from each?

Nondisjunction and Chromosomal Disorders

  1. How it worksHow does a pair of chromosomes failing to separate during meiosis leave one gamete with an extra copy?
  2. Worked exampleFind the number of chromosomes in a gamete when chromosome 21 fails to separate during meiosis I in a human.
  3. Going furtherWhat happens to a fertilized egg's chromosome count when a nondisjunction gamete meets a normal one?
Your turn1 of 2
In a species with a haploid chromosome number of 34, nondisjunction during meiosis I causes one homologous pair to fail to separate, leaving one resulting gamete with an extra copy of that chromosome. How many chromosomes does that nondisjunction gamete have?